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The Power of Vitamin B5 in Skincare: Moisturizing, Barrier Function, Wound Healing, Sources, Usage, Scientific Evidence

Last updated: Aug 2023
In this article:

Benefits of Vitamin B5 for Skincare

Vitamin B5, also known as pantothenic acid, is not only essential for the overall well-being of the body but also for maintaining healthy skin. When it comes to skincare, vitamin B5 offers several benefits, including its moisturizing effects, improved skin barrier function, and wound healing properties. In this guide, we will delve into each of these aspects to give you a better understanding of how vitamin B5 can contribute to healthier and more radiant skin.

Moisturizing Effects:

  • One of the primary benefits of vitamin B5 for skincare is its moisturizing effects.
  • This vitamin is known for its ability to attract and retain moisture in the skin, resulting in improved hydration levels.
  • By incorporating vitamin B5 into your skincare routine, you can combat dry skin, which often leads to flakiness, itchiness, and a dull complexion.
  • To harness the moisturizing effects of vitamin B5, start by including skincare products that contain this vitamin in your regimen.
  • Look for moisturizers, serums, and creams labeled with "panthenol" or "pantothenic acid" on their ingredient lists.
  • These products will help keep your skin well-hydrated, soft, and supple.

Improved Skin Barrier Function:

  • The skin's barrier function serves as a protective layer, shielding it from external environmental aggressors, such as pollutants and harsh weather conditions.
  • Vitamin B5 plays a significant role in enhancing this barrier function, keeping your skin healthy and resilient.
  • To promote an improved skin barrier function, look for skincare products that contain vitamin B5 derivatives, such as panthenol.
  • These derivatives penetrate the skin, reinforce its protective layer, and help prevent moisture loss.
  • With a stronger skin barrier, your skin is better equipped to defend itself against external stressors, resulting in a more vibrant complexion.

Wound Healing Properties:

  • Vitamin B5 is also widely recognized for its remarkable wound healing properties.
  • When applied topically, it aids in accelerating the healing process of damaged skin, such as cuts, burns, and blemishes.
  • Vitamin B5 strengthens the skin's natural ability to repair itself, promoting faster cell regeneration and collagen production.
  • To harness the wound healing properties of vitamin B5, consider using skincare products that contain panthenol or vitamin B5 as an active ingredient.
  • These products are particularly beneficial for individuals with acne-prone or sensitive skin, as they help calm inflammation and promote faster healing of acne breakouts or other skin irritations.
  • In addition to using topical skincare products, ensuring an adequate intake of vitamin B5 in your diet can further support your skin's healing process.
  • Incorporate food sources rich in vitamin B5, including whole grains, avocados, mushrooms, and legumes, into your meals.
  • Alternatively, you can also opt for vitamin B5 supplements after consulting with your healthcare provider.


From its moisturizing effects to improved skin barrier function and wound healing properties, vitamin B5 offers numerous benefits for skincare.

By incorporating vitamin B5 into your daily routine, whether through topical products or a balanced diet, you can achieve healthier and more radiant skin.

Remember to be consistent with your skincare regimen and always choose products that suit your skin type to maximize the benefits of vitamin B5.

Sources of Vitamin B5

Vitamin B5, also known as pantothenic acid, is an essential nutrient that plays a vital role in our body's overall health and well-being. It is required for the metabolism of carbohydrates, proteins, and fats, and it also contributes to the production of energy.

While a deficiency in vitamin B5 is rare, it is still important to ensure that you are getting enough of this vitamin in your diet. Here, we will explore the different sources of vitamin B5, including food sources, supplements, and topical applications.

Food Sources

One of the best ways to ensure you are getting an adequate amount of vitamin B5 is to include foods that are rich in this nutrient in your daily diet. Some excellent food sources of vitamin B5 include:

  • Meat and Poultry: Liver, kidneys, and organ meats are particularly high in vitamin B5.
  • Fish and Seafood: Salmon, tuna, and shellfish, such as mussels and clams, are excellent sources of vitamin B5.
  • Dairy Products: Milk, yogurt, and cheese contain good amounts of vitamin B5. Opt for low-fat or non-fat versions to keep your overall calorie intake in check.
  • Legumes: Lentils, chickpeas, and split peas are not only high in fiber and protein but also a good source of vitamin B5.
  • Whole Grains: Brown rice, whole wheat bread, and whole grain cereals are packed with vitamin B5.
  • Vegetables: Include vegetables such as broccoli, mushrooms, avocados, and sweet potatoes in your meals to boost your vitamin B5 intake.


If you are unable to get enough vitamin B5 through your diet alone, you may consider taking vitamin B5 supplements. These supplements come in various forms, including capsules, tablets, and liquid extracts. It is important to consult with a healthcare professional before starting any new supplement regimen to ensure you are taking the correct dosage and to avoid any potential interactions with other medications.

Topical Applications

Topical applications of vitamin B5 can be beneficial for skin and hair health. You may find skincare products such as creams, lotions, and serums that contain vitamin B5. These products can help hydrate the skin, reduce inflammation, and improve the skin's overall appearance. Some topical applications of vitamin B5 may also promote hair growth and make hair appear healthier and shinier.

It is worth noting that vitamin B5 is water-soluble, which means that any excess amount is excreted through urine. As a result, side effects from consuming excess amounts of vitamin B5 are rare. However, it is essential to follow the recommended daily allowance (RDA) guidelines, which for adults is around 5 mg per day.

Usage and Application of Vitamin B5

Vitamin B5, also known as pantothenic acid, is a versatile ingredient that offers numerous benefits for the skin. It is a popular choice in skincare routines due to its ability to deeply moisturize, soothe, and heal the skin. In this guide, we will explore the different ways you can incorporate vitamin B5 into your skincare routine, its compatibility with other skincare ingredients, and its suitability for different skin types.

Incorporating into Skincare Routine

There are various ways to incorporate vitamin B5 into your skincare routine. One common method is to use a product that contains vitamin B5 as an active ingredient, such as a moisturizer, serum, or facial mask. These products are easily absorbed by the skin and deliver the benefits of vitamin B5 directly.

To maximize the benefits of vitamin B5, it is essential to cleanse your face thoroughly before application. Gently cleanse your face with a mild cleanser and pat it dry. Next, apply a small amount of your chosen vitamin B5 product to your face and gently massage it in using upward circular motions. Include your neck and décolletage areas for a complete skincare routine. Allow the product to absorb fully before moving on to the next step in your routine.

Combination with Other Skincare Ingredients

Vitamin B5 works well with a variety of other skincare ingredients. One popular combination is with hyaluronic acid, a powerful hydrating ingredient. When used together, vitamin B5 and hyaluronic acid create a moisture-locking duo that helps the skin retain hydration, resulting in plump and nourished skin.

Another effective combination is vitamin B5 and niacinamide. Niacinamide helps regulate oil production, reduce inflammation, and improve the overall texture of the skin. When paired with vitamin B5, these two ingredients work together to soothe and calm irritated or sensitive skin while restoring its natural moisture barrier.

Suitability for Different Skin Types

Vitamin B5 is suitable for all skin types, making it a versatile option for everyone. It is particularly beneficial for dry and dehydrated skin, as it helps replenish moisture levels and improve skin elasticity. Its hydrating properties can also assist in reducing the appearance of fine lines and wrinkles.

For those with oily or acne-prone skin, vitamin B5 can help regulate oil production and soothe any inflammation or redness. It is non-comedogenic, meaning it won't clog pores, making it an excellent choice for people prone to breakouts.

Sensitive skin can greatly benefit from the use of vitamin B5 as well. Its soothing and healing properties can reduce redness and irritation, promoting a healthy and calm complexion. Make sure to patch test any new vitamin B5 products if you have sensitive skin to ensure no adverse reactions occur.

Scientific Evidence and Studies on Skin Hydration

Several studies have investigated the effects of different factors on skin hydration. For instance, a study published in the Journal of Dermatological Science found that environmental factors, such as temperature and humidity, significantly affect skin hydration levels. They concluded that low humidity levels can impair the skin's ability to retain moisture, leading to dryness and roughness.

Furthermore, a study published in the International Journal of Cosmetic Science examined the impact of skincare products on skin hydration. They found that moisturizers containing humectant ingredients, such as glycerin and hyaluronic acid, increased skin hydration levels significantly. These humectants attract and bind water, preventing transepidermal water loss and improving skin hydration.

Epidermal Barrier Function

The epidermal barrier is crucial for protecting the skin against external aggressors and maintaining its overall health. Several studies have investigated the factors that influence epidermal barrier function. One study published in the British Journal of Dermatology explored the effects of different cleansers on the skin's barrier function. They found that certain cleansers containing harsh surfactants disrupted the skin's lipid barrier, leading to dehydration and increased transepidermal water loss.

Additionally, research published in the Journal of Investigative Dermatology highlighted the importance of ceramides in maintaining the epidermal barrier function. Ceramides are natural lipids found in the stratum corneum, the outermost layer of the epidermis. Studies have shown that applying skincare products containing ceramides can enhance the skin's barrier function, reducing water loss and improving overall skin health.

Clinical Trials and Research Findings

Numerous clinical trials have been conducted to evaluate the effectiveness of skincare products and treatments on skin hydration and barrier function. For example, a randomized controlled trial published in the Journal of Cosmetic Dermatology compared the effects of a moisturizer containing natural ingredients with a placebo. The trial showed that the moisturizer significantly improved skin hydration and barrier function, reducing roughness and dryness.

Furthermore, research published in the Journal of Drugs in Dermatology focused on the effects of oral supplements on skin hydration. The study found that oral intake of certain nutrients, such as omega-3 fatty acids and hyaluronic acid, improved skin hydration levels and helped maintain the skin's barrier function.


  1. Vitamin B5, also known as pantothenic acid, is a water-soluble vitamin that plays a crucial role in maintaining the health of our skin.

  2. It acts as a humectant, helping to attract and retain moisture in the skin, which improves hydration levels and prevents dryness.

  3. Vitamin B5 also works as an effective skin softener and moisturizer, leaving the skin smoother, softer, and more supple.

  4. It has anti-inflammatory properties that can help calm and soothe irritated skin, making it ideal for those with sensitive or acne-prone skin.

  5. Vitamin B5 promotes skin healing and regeneration, aiding in the repair of damaged skin and supporting the growth of new cells.

  6. It can also help to improve the skin's natural barrier function, protecting against environmental stressors and reducing moisture loss.